01775nas a2200229   4500008004100000022001400041245010400055210006900159260004200228300000900270490000600279520107000285653001401355653002501369653001501394653001801409653000801427653003301435653002001468100002001488856003701508       2016                        eng d  a1927-032100aProfiling Regional Innovation Ecosystems as Functional Collaborative Systems: The Case of Cambridge0 aProfiling Regional Innovation Ecosystems as Functional Collabora  aOttawabTalent First Networkc12/2016  a6-250 v63 aIt has been widely recognized that the national and regional development of innovation ecosystems has been a relatively successful model for regional revitalization, bringing together key actors to perform the relevant technology-driven development processes. The ecosystems have been organized and combine readily public sector interests with private sector business-oriented actions. However, all regions are not uniformly successful, which leaves open the question of how to guide the sub-optimum regional systems closer to the front-runner position. Why do some score better than the others? This article presents both theoretical and practical evidence of global best practice in developing regional innovation hubs and renders a fully integrated innovation hub framework that defines a novel, holistic approach to managing these ecosystems. The framework is tested and validated through a selected case study of Cambridge, United Kingdom, identifying the key ecosystem elements that are necessary for building up a solid foundation for the innovative regions.10aCambridge10ainnovation ecosystem10amanagement10aorchestration10aPPP10apublic–private partnership10asystem thinking1 aViitanen, Jukka  uhttp://timreview.ca/article/1038